HCV Virtual Cascade of Care Cohort

This multi-centre observational prospective cohort study integrates community-based recruitment and data collection with data linkage to inform and enhance scale-up of hepatitis C (HCV) treatment among people who inject substances (PWIS).


Research shows that a large number of individuals infected with HCV do not receive treatment, even though HCV is a curable disease.

By considering how PWIS with differing markers of vulnerability navigate the HCV cascade of care, this study will guide tailored interventions and inclusive policies that ensure all PWIS living with HCV access treatment.


Build a better understanding of the extent to which PWIS across Canada are engaged in HCV care and how this relates to broader patterns of service use and life circumstances in order to improve their access to health care.

Feasibility Study

Pilot projects were conducted in Quebec and Saskatchewan, in partnership with the University of Saskatchewan.

Five Community Partners participated in the feasability study:

Participants recruited in Quebec
Participants recruited in Saskatchewan


The VCCC feasibility study was funded by the Canadian Network on Hepatitis C (CanhepC).

The establishment of the pan-Canadian VCCC Cohort is financed by the Canadian Institutes of Health Research (CIHR) (2019 – 2023)

For more information

For further information about the VCCC study, please contact Manuela Mbacfou at manuela.mbacfou.temgoua.chum@ssss.gouv.qc.ca

Some Preliminary Data from the Quebec Feasibility Study

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